Immunity-diseases of the circulatory System
Immunity-diseases of the circulatory System
Ang pagkontrol sa presyon ay isang napakahalagang gawain, dahil ang pag-inom ng mga tableta na nakakatulong sa pagpapanatili ng normal na mga indikador ay maaaring magbigay ng araw-araw na komportableng buhay, upang maiwasan ang panganib ng hypertensive crisis, atake sa puso, at stroke. Ang mga gamot para sa kontrol ng presyon ay medyo malawakang makukuha sa mga botika, pero tanging ang doktor lang ang makakapili ng tamang gamot na angkop sa therapy. Lahat ng grupo ng gamot para pababain ang presyon ay may iba't ibang mekanismo ng epekto, side effects, at may kaunting posibilidad ng pagkadepende. Ang tamang pagpili ng gamot ay nagbibigay ng mabilis at tuloy-tuloy na resulta, at ang eksperimento sa sarili sa pag-inom ng gamot ay may mataas na posibilidad ng biglaang karamdaman, sakit sa puso at daluyan ng dugo, at sa matinding kaso, maaaring magdulot ng kamatayan.
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Immunity-associated diseases of the cardiovascular system: Pathomechanisms and clinical relevance The circulatory System functions assigned to the supply of the organs with oxygen and nutrients and removal of metabolic waste products are for Survival is essential. In the last decades has shown that a number of diseases of this system are determined not only by conventional risk factors such as hypertension, hyperlipidemia, or Diabetes mellitus, but also by immunological processes are affected. Immune-mediated cardiovascular diseases include a heterogeneous group of diseases in which dysregulation of the immune system leads to an inflammatory response against the body's own structures. Among the most important categories: Rheumatic heart disease, in particular Streptococcus pyogenes infection, occurring in rheumatic fever with the following cardiac involvement (Endo‑, Myo‑ or pericarditis). Here, the phenomenon of molecular Mimikrie plays a Central role: antibodies against bacterial antigens react gewebsstrukturen cross with a Heart. Vasculitis, i.e., inflammation of the blood vessel walls. Systemic vasculitis such as Granulomatosis with Polyangiitis (GPA, formerly Wegener's Granulomatosis) or Polyarteritis nodosa may affect the coronary arteries or other vessels of the circulatory system and lead to Ischemia, Infarction, or aneurysms. Autoimmune‑associated cardiomyopathies, such as dilated cardiomyopathy with proven autoantibodies against the cardiac muscle proteins (such as β‑Adrenoceptors, or Myosin). Atherosclerosis as a chronic inflammatory disease. Meanwhile, atherosclerosis is considered as a purely degenerative process, but rather as a complex process with a crucial involvement of the immune system. Macrophages, T‑lymphocytes and inflammatory cytokines (e.g., TNF‑α, IL‑6) play an important role in Plaque formation and instability. Pathophysiological Mechanisms The common basis of many immune-associated cardiovascular diseases, there is a Dysregulation of the immune response is: Activation of the Inflammasome leads to the release of proinflammatory cytokines and initiates chronic inflammation in the vascular endothelium or the heart muscle. The formation of auto-antibodies against the body's own antigens (e.g., against phospholipids in the case of Antiphospholipid syndrome) may cause thrombus formation and Vascular occlusion. T‑cell‑mediated tissue damage occurs in myocardial inflammation, if the author of attack of active T‑cells, heart muscle cells. Immune complex deposits in the vascular wall (e.g., systemic Lupus erythematosus) can activate the complement system and cause a vasculitis. Clinical implications and therapeutic approaches The diagnostics includes, besides the classical cardiovascular examination (ECG, echocardiography, coronary angiography) also immunological Tests: Determination of autoantibodies (ANA, ANCA, Anti‑Myosin antibody) Measurement of markers of Inflammation (CRP, ESR, IL‑6) Tissue biopsy in vasculitic conditions for histological confirmation The therapy depends on the disease and aims to attenuate the immunological Hyperactivity: Corticosteroids (prednisone) as a basic medication to suppress the inflammation. Immunosuppressants, such as methotrexate, azathioprine or Mycophenolate mofetil for the reduction of the autoimmune reaction. Biologics (e.g., Anti‑TNF‑α antibody, Rituximab) for treatment-resistant forms. Adjuvant cardiovascular medications (beta blockers, ACE inhibitors, anticoagulants) to support the heart function, and thrombosis prophylaxis. Summary Immunity-associated cardiovascular diseases represent a major challenge for clinical medicine. A deeper understanding of the immunopathological mechanisms allows the development of targeted therapies and may improve the prognosis of this group of patients significantly. The close cooperation between cardiologists and rheumatologists/immunologists is of Central importance.
Ginagamit ito bilang biologically active na pampadagdag sa pagkain — dagdag na pinagmumulan ng mga bitamina — B2, B6, C, mga organikong asido — mansanas, succinic, glutamine. Mga sangkap: malic acid, succinic acid, glutamic acid, badan extract, ascorbic acid, bitamina B2, B6. Immunity-diseases of the circulatory System. Ang presyon ng dugo ay isa sa mga pangunahing indikasyon ng kalusugan, na hindi lamang sumasalamin sa puso at sistema ng sirkulasyon, kundi pati na rin sa aktibidad ng mga bato, mga organo ng endokrin, paggawa ng dugo, at ng sistema ng nerbiyos. Kaya naman, walang isang unibersal na gamot laban sa mataas na presyon ng dugo. Hindi ka basta basta puwedeng pumunta sa botika at magtanong ng 'tableta para sa presyon,' kasi agad na tatanungin ng parmasyutiko – anong gamot ang nireseta sa iyo ng doktor?
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http://friz.ch/userfiles/sweating-in-cardiovascular-diseases-4292.xml
http://lampda.co.kr/fckeditor/_upload/9511-15-diseases-of-the-circulatory-system.xml
Ginagamit ito bilang biologically active na pampadagdag sa pagkain — dagdag na pinagmumulan ng mga bitamina — B2, B6, C, mga organikong asido — mansanas, succinic, glutamine. Mga sangkap: malic acid, succinic acid, glutamic acid, badan extract, ascorbic acid, bitamina B2, B6. Kasabay nito, hindi inirerekomenda ang pangmatagalang pag-inom ng mga gamot mula sa kategoryang Diuretics, dahil ang mahahalagang sangkap tulad ng Potassium, Calcium, Magnesium ay mabilis na nailalabas sa katawan kasama ng sobrang tubig at asin. Alinsunod sa katangiang ito, sinasabayan ng mga Diuretics ang pag-inom ng mga gamot na may laman ng mga sangkap na ito. Maaaring ito ay mga vitamin at mineral na complexes, monokomponent, o mga suplemento sa pagkain na may napatunayang klinikal na bisa.
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